SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06004

Signal sequence   MKQKKLALLLALLLASSSASAC

Length  22

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06004.cif

Structure  SPKB06004.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2260.82224

Aliphatic index  146.8181818

Isoelectric point  10.51301932

Charge (pH=7)   2.935124482

Topological polar surface area  876.49

Aromaticity  0

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -7.6941

Hydropathy 



Literature Information


Title  Synthetic signal peptides specifically recognize SecA and stimulate ATPase activity in the absence of preprotein

DOI  10.1074/jbc.273.19.11409,

Publication Year  1998

PubMed ID  9565549,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.