SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06002

Signal sequence   MKAFTSLLCGLGLSTTLA

Length  18

Organism  Saccharomyces cerevisiae

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06002.cif

Structure  SPKB06002.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1827.22744

Aliphatic index  119.4444444

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  685.19

Aromaticity  0.055555556

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -6.6454

Hydropathy 



Literature Information


Title  Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania

DOI  10.1042/bj3310521,

Publication Year  1998

PubMed ID  9531493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.