SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06001

Signal sequence   MDSKGSSQKGSRLLLLLVVSNLLLC

Length  25

Organism  Bos taurus (Bovine)

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5B4W,

Predicted Structure ID  SPKB06001.cif

Structure  SPKB06001.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2675.24064

Aliphatic index  148

Isoelectric point  9.673752869

Charge (pH=7)   1.935862689

Topological polar surface area  1100.29

Aromaticity  0

Average rotatable bonds  3.8

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  39

X logP energy  -11.24163

Hydropathy 



Literature Information


Title  Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania

DOI  10.1042/bj3310521,

Publication Year  1998

PubMed ID  9531493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.