SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06000

Signal sequence   MMTQSIRRSMLTVMATLPLLFSSATL

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06000.cif

Structure  SPKB06000.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2900.56444

Aliphatic index  108.8461538

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1110.76

Aromaticity  0.038461538

Average rotatable bonds  3.692307692

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -10.46356

Hydropathy 



Literature Information


Title  Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania

DOI  10.1042/bj3310521,

Publication Year  1998

PubMed ID  9531493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.