SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05998

Signal sequence   MSVDSSSTHRHRSVAARLVRLAAAGAAVIAAVGTAAAWA

Length  39

Organism  Leishmania chagasi

UniProt ID  NA,

Motif  1..39



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05998.cif

Structure  SPKB05998.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3860.41244

Aliphatic index  100.5128205

Isoelectric point  12.50005554

Charge (pH=7)   3.18023572

Topological polar surface area  1668.78

Aromaticity  0.025641026

Average rotatable bonds  3.128205128

Number of hydrogen bond donors  63

Number of hydrogen bond acceptors  55

X logP energy  -21.57992

Hydropathy 



Literature Information


Title  Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania

DOI  10.1042/bj3310521,

Publication Year  1998

PubMed ID  9531493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.