General Information
SPKB ID SPKB05992
Signal sequence MMKRNLLAVIVPALLVAGGTANA
Length 23
Organism Artificial
UniProt ID NA,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05992.cif
Physicochemical Information
Molecular weight 2323.88404
Aliphatic index 144.3478261
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 889.06
Aromaticity 0
Average rotatable bonds 3.304347826
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -6.83903
Hydropathy
Literature Information
Title The hydrophobic region of signal peptides is a determinant for SRP recognition and protein translocation across the ER membrane
DOI 10.1093/oxfordjournals.jbchem.a021583,
Publication Year 1997
PubMed ID 9089400,
Patent ID NA,