SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05991

Signal sequence   MPMFRIRLPKPAALIAAGGIGACIATVAVPSAYA

Length  34

Organism  Streptomyces cacaoi

UniProt ID  NA,

Motif  1..34



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05991.cif

Structure  SPKB05991.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3399.17754

Aliphatic index  112.3529412

Isoelectric point  10.45681222

Charge (pH=7)   2.934857513

Topological polar surface area  1198.97

Aromaticity  0.058823529

Average rotatable bonds  3

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  44

X logP energy  -8.26096

Hydropathy 



Literature Information


Title  Roles of the signal peptide and mature domains in the secretion and maturation of the neutral metalloprotease from Streptomyces cacaoi

DOI  10.1042/bj3210029,

Publication Year  1997

PubMed ID  9003398,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.