SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05990

Signal sequence   MLSRAIFRNPVINRTLLRAR

Length  20

Organism  Yeast

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6GIQ,

Predicted Structure ID  SPKB05990.cif

Structure  SPKB05990.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2397.91674

Aliphatic index  122

Isoelectric point  13.10207708

Charge (pH=7)   4.997967743

Topological polar surface area  1043.57

Aromaticity  0.05

Average rotatable bonds  4

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  31

X logP energy  -9.52195

Hydropathy 



Literature Information


Title  A mitochondrial signal peptide from Neurospora crassa increases the permeability of isolated rat liver mitochondria

DOI  10.1006/abbi.1996.0533,

Publication Year  1996

PubMed ID  8951036,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.