SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05986

Signal sequence   MRTLRPQARAPRGLLAALGAVLAAFALVSSLVTAAAPAQA

Length  40

Organism  Streptomyces lividans

UniProt ID  NA,

Motif  1..40



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05986.cif

Structure  SPKB05986.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3972.75434

Aliphatic index  122.5

Isoelectric point  12.97714556

Charge (pH=7)   3.997971054

Topological polar surface area  1586.55

Aromaticity  0.025

Average rotatable bonds  3.1

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  52

X logP energy  -16.03762

Hydropathy 



Literature Information


Title  Effect of signal peptide alterations and replacement on export of xylanase A in Streptomyces lividans

DOI  10.1128/aem.62.1.109-114.1996,

Publication Year  1996

PubMed ID  8572687,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.