General Information
SPKB ID SPKB05984
Signal sequence MKKAKAIFLFILIVSGFLLVAC
Length 22
Organism Escherichia coli
UniProt ID NA,
Motif 1..22
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Cytoplasmic membrane
Secretion efficiency NA
Type Sec/SPII
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05984.cif
Physicochemical Information
Molecular weight 2426.14624
Aliphatic index 164.0909091
Isoelectric point 10.51301932
Charge (pH=7) 2.935124482
Topological polar surface area 772.71
Aromaticity 0.136363636
Average rotatable bonds 3.727272727
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 29
X logP energy 0.6952
Hydropathy 
Literature Information
Title A lipoprotein signal peptide plus a cysteine residue at the amino-terminal end of the periplasmic protein beta-lactamase is sufficient for its lipid modification, processing and membrane localization in Escherichia coli
DOI 10.1111/j.1574-6968.1993.tb06127.x,
Publication Year 1993
PubMed ID 8514122,
Patent ID NA,
