SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05983

Signal sequence   MKKAKAIFLFILIVSGFLLVG

Length  21

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cytoplasmic membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05983.cif

Structure  SPKB05983.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2308.98054

Aliphatic index  167.1428571

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  743.61

Aromaticity  0.142857143

Average rotatable bonds  3.761904762

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  0.8921

Hydropathy 



Literature Information


Title  A lipoprotein signal peptide plus a cysteine residue at the amino-terminal end of the periplasmic protein beta-lactamase is sufficient for its lipid modification, processing and membrane localization in Escherichia coli

DOI  10.1111/j.1574-6968.1993.tb06127.x,

Publication Year  1993

PubMed ID  8514122,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.