SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05968

Signal sequence   IQASFRGHITRKKL

Length  14

Organism  Rattus norvegicus (Rat)

UniProt ID  NA,

Motif  1..14



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05968.cif

Structure  SPKB05968.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1654.97904

Aliphatic index  90.71428571

Isoelectric point  12.53174777

Charge (pH=7)   4.0882967

Topological polar surface area  729.69

Aromaticity  0.071428571

Average rotatable bonds  4.142857143

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  23

X logP energy  -6.87806

Hydropathy 



Literature Information


Title  Identification of binding proteins for nuclear localization signals of the glucocorticoid and thyroid hormone receptors

DOI  10.1210/endo.133.6.8243301,

Publication Year  1993

PubMed ID  8243301,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.