General Information
SPKB ID SPKB05962
Signal sequence MNMKKLATLVSAVALSATVSANAMA
Length 25
Organism Escherichia coli
UniProt ID P02925,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05962.cif
Physicochemical Information
Molecular weight 2494.02124
Aliphatic index 109.6
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 1001.09
Aromaticity 0
Average rotatable bonds 3.36
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 38
X logP energy -11.7143
Hydropathy 
Literature Information
Title Escherichia coli signal peptides direct inefficient secretion of an outer membrane protein (OmpA) and periplasmic proteins (maltose-binding protein, ribose-binding protein, and alkaline phosphatase) in Bacillus subtilis
DOI 10.1128/jb.176.10.3013-3020.1994,
Publication Year 1994
PubMed ID 8188602,
Patent ID NA,
