SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05948

Signal sequence   MASSLSMRSLLILVLCFIPLAA

Length  22

Organism  Gallus gallus (Chicken)

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05948.cif

Structure  SPKB05948.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2349.97704

Aliphatic index  168.6363636

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  808.45

Aromaticity  0.045454545

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -3.91903

Hydropathy 



Literature Information


Title  Effect of chicken lysozyme signal peptide alterations on secretion of human lysozyme in Saccharomyces cerevisiae

DOI  10.1139/o93-058,

Publication Year  1993

PubMed ID  8123256,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.