SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05945

Signal sequence   MALDVDSMRSLLILVLCFIPLAA

Length  23

Organism  Gallus gallus (Chicken)

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05945.cif

Structure  SPKB05945.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2505.13044

Aliphatic index  173.9130435

Isoelectric point  4.10922387

Charge (pH=7)   -1.06310076

Topological polar surface area  871.69

Aromaticity  0.043478261

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -2.81343

Hydropathy 



Literature Information


Title  Effect of chicken lysozyme signal peptide alterations on secretion of human lysozyme in Saccharomyces cerevisiae

DOI  10.1139/o93-058,

Publication Year  1993

PubMed ID  8123256,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.