SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05944

Signal sequence   MALDPGEGVDSMRSLLILVLCFIPLAA

Length  27

Organism  Gallus gallus (Chicken)

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05944.cif

Structure  SPKB05944.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2845.46644

Aliphatic index  148.1481481

Isoelectric point  3.876001358

Charge (pH=7)   -2.061325637

Topological polar surface area  1016.6

Aromaticity  0.037037037

Average rotatable bonds  3.37037037

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  37

X logP energy  -5.24043

Hydropathy 



Literature Information


Title  Effect of chicken lysozyme signal peptide alterations on secretion of human lysozyme in Saccharomyces cerevisiae

DOI  10.1139/o93-058,

Publication Year  1993

PubMed ID  8123256,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.