SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05941

Signal sequence   MKAFTSLLCGLGLSTTLARA

Length  20

Organism  Saccharomyces cerevisiae

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05941.cif

Structure  SPKB05941.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2054.49374

Aliphatic index  112.5

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  805.29

Aromaticity  0.05

Average rotatable bonds  3.4

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -8.39263

Hydropathy 



Literature Information


Title  Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex

DOI  10.1083/jcb.126.4.935,

Publication Year  1994

PubMed ID  8051213,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.