SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05940

Signal sequence   MNSPKKDIHTPPLKYPGGQHRGASCCFVFIMCLLYRICGICGDPRGM

Length  47

Organism  Saccharomyces cerevisiae

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05940.cif

Structure  SPKB05940.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5213.25454

Aliphatic index  66.38297872

Isoelectric point  8.78259082

Charge (pH=7)   3.868226006

Topological polar surface area  1941.02

Aromaticity  0.085106383

Average rotatable bonds  3.510638298

Number of hydrogen bond donors  71

Number of hydrogen bond acceptors  73

X logP energy  -17.12849

Hydropathy 



Literature Information


Title  Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex

DOI  10.1083/jcb.126.4.935,

Publication Year  1994

PubMed ID  8051213,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.