SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05899

Signal sequence   MMITLRKLPLAVAVAADVMSAQAMA

Length  25

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05899.cif

Structure  SPKB05899.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2603.25354

Aliphatic index  125.2

Isoelectric point  9.695024739

Charge (pH=7)   0.998132438

Topological polar surface area  961.7

Aromaticity  0

Average rotatable bonds  3.44

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  36

X logP energy  -6.65063

Hydropathy 



Literature Information


Title  Effect of charged residue substitutions on the thermodynamics of signal peptide-lipid interactions for the Escherichia coli LamB signal sequence

DOI  10.1016/S0006-3495(94)80628-9,

Publication Year  1994

PubMed ID  7819487,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.