SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05887

Signal sequence   AAKGAQVESVQMSGERKTEGNNGRRKMMFAAAAAAICSVAGVATA

Length  45

Organism  Gossypium hirsutum

UniProt ID  NA,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05887.cif

Structure  SPKB05887.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4498.14844

Aliphatic index  61.11111111

Isoelectric point  10.494581

Charge (pH=7)   2.940439916

Topological polar surface area  1992.89

Aromaticity  0.022222222

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  71

Number of hydrogen bond acceptors  68

X logP energy  -27.98129

Hydropathy 



Literature Information


Title  A new type of signal peptide: central role of a twin-arginine motif in transfer signals for the delta pH-dependent thylakoidal protein translocase

DOI  10.1002/j.1460-2075.1995.tb07272.x,

Publication Year  1995

PubMed ID  7796800,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.