SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05876

Signal sequence   MKKTAIAIAVALAGFA

Length  16

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..16



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05876.cif

Structure  SPKB05876.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1575.97324

Aliphatic index  128.75

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  572.09

Aromaticity  0.0625

Average rotatable bonds  3.25

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  21

X logP energy  -3.15

Hydropathy 



Literature Information


Title  Permissible peptide insertions surrounding the signal peptide-mature protein junction of the ClpG prepilin: CS31A fimbriae of Escherichia coli as carriers of foreign sequences

DOI  10.1016/0378-1119(94)90229-1,

Publication Year  1994

PubMed ID  7523252,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.