SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05874

Signal sequence   MKKTLIALAVAVSAVSGAAHA

Length  21

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cytoplasmic membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05874.cif

Structure  SPKB05874.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2009.43814

Aliphatic index  130.4761905

Isoelectric point  10.80542203

Charge (pH=7)   2.088303323

Topological polar surface area  786.73

Aromaticity  0

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -7.6864

Hydropathy 



Literature Information


Title  Permissible peptide insertions surrounding the signal peptide-mature protein junction of the ClpG prepilin: CS31A fimbriae of Escherichia coli as carriers of foreign sequences

DOI  10.1016/0378-1119(94)90229-1,

Publication Year  1994

PubMed ID  7523252,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.