SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05873

Signal sequence   MKFLVNVALVFMVVISIAAPEPEPAPEP

Length  28

Organism  Apis mellifera (Honeybee)

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05873.cif

Structure  SPKB05873.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3009.65554

Aliphatic index  121.7857143

Isoelectric point  3.980054623

Charge (pH=7)   -1.996985366

Topological polar surface area  1006.31

Aromaticity  0.071428571

Average rotatable bonds  3.178571429

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  37

X logP energy  -2.8544

Hydropathy 



Literature Information


Title  Cleavage of honeybee prepromelittin by an endoprotease from rat liver microsomes: identification of intact signal peptide

DOI  10.1073/pnas.79.7.2260,

Publication Year  1982

PubMed ID  7048315,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.