SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05872

Signal sequence   MKATKLVLGAVILGSTLLAA

Length  20

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05872.cif

Structure  SPKB05872.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1970.48504

Aliphatic index  166

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  728.95

Aromaticity  0

Average rotatable bonds  3.35

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -4.6945

Hydropathy 



Literature Information


Title  Requirement for signal peptide cleavage of Escherichia coli prolipoprotein

DOI  10.1126/science.6344218,

Publication Year  1983

PubMed ID  6344218,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.