SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05871

Signal sequence   MKTIG

Length  5

Organism  Influenza virus

UniProt ID  NA,

Motif  1..5



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05871.cif

Structure  SPKB05871.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  548.69834

Aliphatic index  78

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  225.97

Aromaticity  0

Average rotatable bonds  3.8

Number of hydrogen bond donors  8

Number of hydrogen bond acceptors  9

X logP energy  -1.7221

Hydropathy 



Literature Information


Title  Defects in functional expression of an influenza virus hemagglutinin lacking the signal peptide sequences

DOI  10.1073/pnas.80.12.3563,

Publication Year  1983

PubMed ID  6304718,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.