SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05870

Signal sequence   MKTIIALSYIFCLVLG

Length  16

Organism  Influenza virus

UniProt ID  NA,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05870.cif

Structure  SPKB05870.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1785.27634

Aliphatic index  170.625

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  586.53

Aromaticity  0.125

Average rotatable bonds  3.625

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -0.3698

Hydropathy 



Literature Information


Title  Defects in functional expression of an influenza virus hemagglutinin lacking the signal peptide sequences

DOI  10.1073/pnas.80.12.3563,

Publication Year  1983

PubMed ID  6304718,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.