SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05845

Signal sequence   MIKFSATLLATLIAASVNA

Length  19

Organism  Escherichia coli

UniProt ID  P08331,

Motif  1..19



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05845.cif

Structure  SPKB05845.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1935.35254

Aliphatic index  144.2105263

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  737.15

Aromaticity  0.052631579

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -6.1429

Hydropathy 



Literature Information


Title  Signal peptide amino acid sequences in Escherichia coli contain information related to final protein localization. A multivariate data analysis

DOI  10.1002/j.1460-2075.1987.tb04825.x,

Publication Year  1987

PubMed ID  3556168,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.