SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05837

Signal sequence   MKIKTGARILALSALTTMMFSASALA

Length  26

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6P6W,

Predicted Structure ID  SPKB05837.cif

Structure  SPKB05837.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2698.33634

Aliphatic index  113.0769231

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1026.14

Aromaticity  0.038461538

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  39

X logP energy  -9.31173

Hydropathy 



Literature Information


Title  Signal peptide amino acid sequences in Escherichia coli contain information related to final protein localization. A multivariate data analysis

DOI  10.1002/j.1460-2075.1987.tb04825.x,

Publication Year  1987

PubMed ID  3556168,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.