SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05836

Signal sequence   MKVMRTTVATVVAATLSMSAFSVFA

Length  25

Organism  Escherichia coli

UniProt ID  P0AG82,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05836.cif

Structure  SPKB05836.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2620.17924

Aliphatic index  93.6

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  991.25

Aromaticity  0.08

Average rotatable bonds  3.36

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -9.90383

Hydropathy 



Literature Information


Title  Signal peptide amino acid sequences in Escherichia coli contain information related to final protein localization. A multivariate data analysis

DOI  10.1002/j.1460-2075.1987.tb04825.x,

Publication Year  1987

PubMed ID  3556168,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.