SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05833

Signal sequence   MGPRALLVLLMATAWHAQG

Length  19

Organism  Feline sarcoma virus (strain McDonough)

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05833.cif

Structure  SPKB05833.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2036.48394

Aliphatic index  118.421052631579

Isoelectric point  10.5517587037757

Charge (pH=7)   1.08889007900159

Topological polar surface area  748.02

Aromaticity  0.0526315789473684

Average rotatable bonds  3.31578947368421

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -4.08072999999995

Hydropathy 



Literature Information


Title  The amino-terminal domain of the v-fms oncogene product includes a functional signal peptide that directs synthesis of a transforming glycoprotein in the absence of feline leukemia virus gag sequences

DOI  10.1128/JVI.59.2.224-233.1986,

Publication Year  1986

PubMed ID  3525854,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.