General Information
SPKB ID SPKB05831
Signal sequence MDLVVVLGLCLSCLLLLSLWKQSHGRSDGKSVKKRA
Length 36
Organism Oryctolagus cuniculus (Rabbit)
UniProt ID NA,
Motif 1..36
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05831.cif
Physicochemical Information
Molecular weight 3954.80954
Aliphatic index 132.5
Isoelectric point 10.34153488
Charge (pH=7) 3.964650169
Topological polar surface area 1573.01
Aromaticity 0.027777778
Average rotatable bonds 3.833333333
Number of hydrogen bond donors 59
Number of hydrogen bond acceptors 55
X logP energy -13.15926
Hydropathy
Literature Information
Title Positive charges at the NH2 terminus convert the membrane-anchor signal peptide of cytochrome P-450 to a secretory signal peptide
Publication Year 1988
PubMed ID 3422456,
Patent ID NA,