SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05829

Signal sequence   MKIKTGARILALSALTTMMFSASALAKI

Length  28

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6P6W,

Predicted Structure ID  SPKB05829.cif

Structure  SPKB05829.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2939.66984

Aliphatic index  118.9285714

Isoelectric point  11.92450937

Charge (pH=7)   3.997095887

Topological polar surface area  1110.36

Aromaticity  0.035714286

Average rotatable bonds  3.642857143

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -9.16703

Hydropathy 



Literature Information


Title  Mutational alterations affecting the export competence of a truncated but fully functional maltose-binding protein signal peptide

DOI  10.1128/jb.169.6.2345-2351.1987,

Publication Year  1987

PubMed ID  3294786,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.