SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05827

Signal sequence   MEDTNLVLGAVILGSTLLAGC

Length  21

Organism  Saccharomyces cerevisiae DMM1-15A

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05827.cif

Structure  SPKB05827.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2090.47784

Aliphatic index  148.571428571429

Isoelectric point  3.55006587086245

Charge (pH=7)   -2.0617688096318

Topological polar surface area  823.7

Aromaticity  0

Average rotatable bonds  3.28571428571429

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -7.73139999999994

Hydropathy 



Literature Information


Title  Defective Escherichia coli signal peptides function in yeast

DOI  10.1111/j.1365-2958.1988.tb00022.x,

Publication Year  1988

PubMed ID  3288832,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.