General Information
SPKB ID SPKB05821
Signal sequence MPSWALFMVTSCLLLAPQNLAQVSS
Length 25
Organism Homo sapiens (Human)
UniProt ID P40238,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05821.cif
Physicochemical Information
Molecular weight 2708.24414
Aliphatic index 113.2
Isoelectric point 5.922539791
Charge (pH=7) -0.063990417
Topological polar surface area 990.35
Aromaticity 0.08
Average rotatable bonds 3.32
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 37
X logP energy -8.1928
Hydropathy 
Literature Information
Title Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.
Publication Year 1992
PubMed ID 1608974,
Patent ID NA,
