SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05769

Signal sequence   MGKHILLLPLGLSLLMSSLLA

Length  21

Organism  Rattus norvegicus (Rat)

UniProt ID  P81828,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05769.cif

Structure  SPKB05769.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2220.84354

Aliphatic index  190.4761905

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  751.92

Aromaticity  0

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  29

X logP energy  -2.0779

Hydropathy 



Literature Information


Title  The characterisation of novel secreted Ly-6 proteins from rat urine by the combined use of two-dimensional gel electrophoresis, microbore high performance liquid chromatography and expressed sequence tag data.

DOI  10.1002/1615-9861(200202)2:2<187::aid-prot187>3.0.co;2-a,

Publication Year  2002

PubMed ID  11840564,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.