SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05765

Signal sequence   MKRLIMATMVTAILASSTVWA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P76520,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05765.cif

Structure  SPKB05765.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2294.85754

Aliphatic index  120.952381

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  850.18

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -5.82713

Hydropathy 



Literature Information


Title  Overexpression of the response regulator evgA of the two-component signal transduction system modulates multidrug resistance conferred by multidrug resistance transporters.

DOI  10.1128/JB.183.4.1455-1458.2001,

Publication Year  2001

PubMed ID  11157960,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.