SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05762

Signal sequence   MPALLFYLLGFCLLQGQVTG

Length  20

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P51456,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05762.cif

Structure  SPKB05762.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2184.68254

Aliphatic index  136.5

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  734.07

Aromaticity  0.15

Average rotatable bonds  3.4

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -2.0092

Hydropathy 



Literature Information


Title  Expression of a preprorelaxin-like gene during squamous differentiation of rabbit tracheobronchial epithelial cells and its suppression by retinoic acid.

DOI  NA,

Publication Year  1992

PubMed ID  1339318,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.