SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05761

Signal sequence   MTRQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTTVKA

Length  41

Organism  Streptococcus pyogenes serotype M1

UniProt ID  P50470,

Motif  1..41



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05761.cif

Structure  SPKB05761.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4354.09424

Aliphatic index  80.97560976

Isoelectric point  11.88882193

Charge (pH=7)   6.995652093

Topological polar surface area  1898.97

Aromaticity  0.048780488

Average rotatable bonds  3.658536585

Number of hydrogen bond donors  68

Number of hydrogen bond acceptors  65

X logP energy  -24.07456

Hydropathy 



Literature Information


Title  The gene sequence and some properties of protein H. A novel IgG-binding protein.

DOI  NA,

Publication Year  1990

PubMed ID  2332638,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.