SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05760

Signal sequence   MKAKKYENQIYNENGRRCQRHGRRLAIA

Length  28

Organism  Escherichia coli

UniProt ID  P46739,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05760.cif

Structure  SPKB05760.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3404.92174

Aliphatic index  52.5

Isoelectric point  11.09900211

Charge (pH=7)   6.027866433

Topological polar surface area  1595.77

Aromaticity  0.071428571

Average rotatable bonds  4.321428571

Number of hydrogen bond donors  58

Number of hydrogen bond acceptors  49

X logP energy  -17.91585

Hydropathy 



Literature Information


Title  Genetic analysis of the gene cluster encoding nonfimbrial adhesin I from an Escherichia coli uropathogen.

DOI  10.1128/iai.61.6.2505-2512.1993,

Publication Year  1993

PubMed ID  8099066,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.