SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05756

Signal sequence   MLSSVALRYLLVLSLAFLAVVTS

Length  23

Organism  Lymnaea stagnalis (Great pond snail) (Helix stagnalis)

UniProt ID  P42579,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05756.cif

Structure  SPKB05756.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2467.04844

Aliphatic index  182.173913

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  886.8

Aromaticity  0.086956522

Average rotatable bonds  3.434782609

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -4.37233

Hydropathy 



Literature Information


Title  The sodium influx stimulating peptide of the pulmonate freshwater snail Lymnaea stagnalis.

DOI  10.1016/0196-9781(93)90114-v,

Publication Year  1993

PubMed ID  8234026,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.