SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05751

Signal sequence   MKKNLLITSVLAMATVSGSVLA

Length  22

Organism  Escherichia coli

UniProt ID  P33781,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Fimbrium

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05751.cif

Structure  SPKB05751.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2247.78034

Aliphatic index  141.8181818

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  870.7

Aromaticity  0

Average rotatable bonds  3.5

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -8.1532

Hydropathy 



Literature Information


Title  Characterization and molecular cloning of the PCF8775 CS5 antigen from an enterotoxigenic Escherichia coli 0115:H40 isolated in Central Australia.

DOI  10.1111/j.1365-2958.1989.tb00175.x,

Publication Year  1989

PubMed ID  2568574,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.