SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05745

Signal sequence   MKKKIISAILMSTVILSAAAPLSGVYA

Length  27

Organism  Lactococcus lactis subsp. cremoris (strain MG1363)

UniProt ID  P22865,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05745.cif

Structure  SPKB05745.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2777.46024

Aliphatic index  141.1111111

Isoelectric point  10.64292272

Charge (pH=7)   2.996248784

Topological polar surface area  1010.57

Aromaticity  0.037037037

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  39

X logP energy  -6.9336

Hydropathy 



Literature Information


Title  Cloning of usp45, a gene encoding a secreted protein from Lactococcus lactis subsp. lactis MG1363.

DOI  10.1016/0378-1119(90)90428-t,

Publication Year  1990

PubMed ID  2123812,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.