SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05741

Signal sequence   HLALLLILENQASG

Length  14

Organism  Cavia porcellus (Guinea pig)

UniProt ID  P16531,

Motif  <1..14



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05741.cif

Structure  SPKB05741.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1491.75044

Aliphatic index  181.4285714

Isoelectric point  5.363507222

Charge (pH=7)   -0.909331487

Topological polar surface area  614.01

Aromaticity  0

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  20

X logP energy  -4.3877

Hydropathy 



Literature Information


Title  Androgens affect the processing of secretory protein precursors in the guinea pig seminal vesicle. II. Identification of conserved sites for protein processing.

DOI  10.1210/mend-3-11-1797,

Publication Year  1989

PubMed ID  2691882,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.