SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05737

Signal sequence   MKVVIFIFALLATICAAFA

Length  19

Organism  Apis mellifera (Honeybee)

UniProt ID  P15450,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05737.cif

Structure  SPKB05737.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2042.61184

Aliphatic index  159.4736842

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  633.37

Aromaticity  0.157894737

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  0.6875

Hydropathy 



Literature Information


Title  Isolation and characterization of abaecin, a major antibacterial response peptide in the honeybee (Apis mellifera).

DOI  10.1111/j.1432-1033.1990.tb15315.x,

Publication Year  1990

PubMed ID  2298215,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.