SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05718

Signal sequence   METDTLLLWVLLLWVPGSTG

Length  20

Organism  Mus musculus (Mouse)

UniProt ID  P01658,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  4KUC,

Predicted Structure ID  SPKB05718.cif

Structure  SPKB05718.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2244.67394

Aliphatic index  146

Isoelectric point  3.550073557

Charge (pH=7)   -1.999794094

Topological polar surface area  794.53

Aromaticity  0.1

Average rotatable bonds  3.4

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.3576

Hydropathy 



Literature Information


Title  Mouse immunoglobulin chains. Partial amino acid sequence of a kappa chain.

DOI  10.1021/bi00728a027,

Publication Year  1973

PubMed ID  4120629,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.