SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05713

Signal sequence   MKNYLSFGMFALLFALTFGTVNSVQA

Length  26

Organism  Streptococcus dysgalactiae subsp. equisimilis (Streptococcus equisimilis)

UniProt ID  P00779,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05713.cif

Structure  SPKB05713.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2871.40484

Aliphatic index  93.84615385

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  1047.26

Aromaticity  0.192307692

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  38

X logP energy  -7.346

Hydropathy 



Literature Information


Title  Complete amino acid sequence of streptokinase and its homology with serine proteases.

DOI  10.1021/bi00269a001,

Publication Year  1982

PubMed ID  6760891,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.