SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05708

Signal sequence   MKNKFAALVITLFVLVLA

Length  18

Organism  Scolopendra mutilans (Chinese red-headed centipede) (Scolopendra subspinipes mutilans)

UniProt ID  I6S7I0,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05708.cif

Structure  SPKB05708.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1991.54934

Aliphatic index  173.3333333

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  673.38

Aromaticity  0.111111111

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -0.3492

Hydropathy 



Literature Information


Title  Chemical punch packed in venoms makes centipedes excellent predators.

DOI  10.1074/mcp.M112.018853,

Publication Year  2012

PubMed ID  22595790,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.