SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05695

Signal sequence   MRLHHLLLALLFLVLSAGSGFTQG

Length  24

Organism  Bubalus bubalis (Domestic water buffalo)

UniProt ID  A3RJ36,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05695.cif

Structure  SPKB05695.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2595.14404

Aliphatic index  150.4166667

Isoelectric point  10.55350111

Charge (pH=7)   1.17979917

Topological polar surface area  955.66

Aromaticity  0.083333333

Average rotatable bonds  3.541666667

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -5.42823

Hydropathy 



Literature Information


Title  Beta-defensin antibiotic peptides in the innate immunity of the buffalo: in vivo and in vitro studies.

DOI  10.1177/026119290803600404,

Publication Year  2008

PubMed ID  18826332,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.