SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05692

Signal sequence   MARMAMMILCVVLTCMVVATPYTEA

Length  25

Organism  Lactuca sativa (Garden lettuce)

UniProt ID  A0A2J6KL39,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05692.cif

Structure  SPKB05692.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2749.49064

Aliphatic index  109.2

Isoelectric point  6.133775205

Charge (pH=7)   -0.125043735

Topological polar surface area  933.05

Aromaticity  0.04

Average rotatable bonds  3.48

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  39

X logP energy  -4.77453

Hydropathy 



Literature Information


Title  Lettuce anaphylaxis: identification of a lipid transfer protein as the major allergen.

DOI  10.1034/j.1398-9995.2003.00097.x,

Publication Year  2003

PubMed ID  12757453,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.