SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05691

Signal sequence   MSSPLRMDVTFLLAAIAVTWVCGLK

Length  25

Organism  Conus victoriae (Queen Victoria cone)

UniProt ID  A0A0F7YYX3,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05691.cif

Structure  SPKB05691.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2723.34564

Aliphatic index  124.8

Isoelectric point  8.545113874

Charge (pH=7)   0.936157722

Topological polar surface area  974.86

Aromaticity  0.08

Average rotatable bonds  3.44

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -5.55483

Hydropathy 



Literature Information


Title  Hormone-like peptides in the venoms of marine cone snails.

DOI  10.1016/j.ygcen.2015.07.012,

Publication Year  2017

PubMed ID  26301480,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.